Mitochondrial disorders

Mitochondrial disorders

Mitochondria

mitochondrial disorder

While the exact causes of autism are still unknown, researchers have recently uncovered a mysterious link between autism and mitochondrial disorders. Mitochondrial disorders are caused by mutations in the mitochondria, which are the parts of our cells that produce energy, and can lead to a wide range of symptoms. This link has made it possible to identify and treat some cases of autism, offering hope to those affected by this condition. In this blog post, we’ll discuss the intriguing connection between autism and mitochondrial disorders and what this could mean for those living with autism.

Mitochondria

The human body requires energy in order to function, and mitochondria are what provide that energy. We digest sugar, protein, and fat into molecules that reach every cell in our body. ATP is the fuel that is used by the body, and mitochondria are little factories within cells that convert these food molecules into energy molecules called ATP. 
Mitochondria are also called the energy-producing powerhouses of the body. They are vital to our survival as they produce energy in the form of ATP (adenosine triphosphate) from the food we eat. This process is called cellular respiration. Mitochondria produce more than 90% of the energy needed by the body to sustain life and support organ function. Mitochondrial dysfunction results in excessive fatigue and other symptoms that are common in almost every chronic disease, from Alzheimer’s disease and cardiovascular disease to diabetes to autism.

Mitochondrial disorder

The mitochondrial disorder can strike both infants and children of all ages and yet is NOT KNOWN what causes the dysfunction in the mitochondria in the first place. They are commonly born with a range of difficulties from lack of muscle tone to lack of strength and poor appetite, difficulty sucking and high tolerance to pain.
Some babies might not show noticeable symptoms right away. For example, when the body is under a significant amount of stress, it requires even more energy. Though a child can get very sick if mitochondria are dysfunctional, there are times when you’ll see problems developing with the child’s neurology if there’s a prolonged illness.
Yes, vaccines are also stressful for the body, and in the case of a small child who, for some reason, has a genetic predisposition to the mitochondrial disorder, it is possible that the child’s development stops after vaccination
At least 50% of children living with autism has mitochondrial disfunction.

Mitochondrial disorders are a group of complex and potentially life-threatening illnesses caused by mutations in the mitochondrial DNA. Mitochondria are tiny organelles found inside our cells that play a key role in energy production. They convert energy from food into a form that our bodies can use to function normally.

When the mitochondrial DNA is mutated, the resulting disorder can affect any part of the body, including the heart, brain, muscles, or other organs. Symptoms can vary from person to person, but can include seizures, developmental delays, movement and coordination problems, muscle weakness, vision and hearing loss, and organ failure. In some cases, these disorders may be fatal.
The exact cause of mitochondrial disorders is unknown, but certain genetic factors can increase an individual’s risk. It is important to note that not all people with mitochondrial disorders will develop autism, but research has shown that there may be a link between the two conditions.
Abnormalities of mitochondrial function could affect about 80% of children with ASD. 

Sympoms of mitochondrial dysfunction

Depending on which cells in the body are affected by the malfunctioning of the mitochondria, it causes varying symptoms. In general, mitochondrial disease causes more severe symptoms when the cell makers in the muscles, brain, or nerves malfunction because these cells use more energy than other cells in the body. In general, symptoms can range from mild to severe, affect one or more organs, and appear at any age. Even people with the same mitochondrial disease may have different symptoms. In addition to both symptoms and severity, the onset of the disease (appearance of symptoms) also varies from person to person.

The most common symptoms are fatigue, but brain fog is also common when the mitochondria in the brain are not working properly.

Other symptoms may include:

  • pain
  • mood disorders
  • anxiety
  • depression
  • concentration disorder

Most chronic diseases/conditions are also linked to mitochondrial dysfunction, such as:

  • cardiovascular diseases
  • lung disease
  • vision and hearing problems
  • learning disabilities
  • autism
  • liver and kidney disease
  • digestive system diseases and symptoms
  • diabetes
  • neurological diseases (including dementia)
  • movement disorders

The Hannah Poling affair

During Hannah’s first 18 months, she suffered an adverse reaction to the 18-month-old vaccine, causing severe neurological and autistic symptoms. Hannah was 19 months when she received five vaccinations (diperte, influenza B, MMR, varicella, and inactivated polio). Hannah was a playful, interactive, and communicative baby two days prior to becoming lethargic, irritable, and feverish two days later. Several days after vaccination, he developed varicella-induced rashes.
 
Hannah was diagnosed with mitochondrial enzyme deficiency encephalopathy months later due to a delay in neurological and psychological development. The signs Hannah displayed all exhibited characteristics of autism spectrum disorder, including language and communication difficulties. It is common for children with mitochondrial enzyme deficiencies to develop neurological symptoms during the first and second years of their lives, but Hannah’s parents believed vaccines led to her disease.
His case in court was successful, though it’s unclear whether the little girl had a mitochondrial disorder prior to the vaccination, or if it was caused by a vaccination reaction.

If the child has a mitochondrial enzyme deficiency, the vaccines can cause developmental declines.

Biomedical specialists believe that mitochondrial problems can be very common in autism; however, there are treatments that can improve mitochondrial disorders.

It would be nice if mitochondrial testing could become part of normal neonatal screening to find out which babies may be more sensitive to heavy metals and chemicals — whether they have “only” mitochondrial dysfunction or mitochondria are functioning completely abnormally — and preventive measures could be taken to protect children.

If the child has a mitochondrial enzyme deficiency, the vaccines can cause developmental declines.

Biomedical specialists believe that mitochondrial problems can be very common in autism; however, there are treatments that can improve mitochondrial disorders.

It would be nice if mitochondrial testing could become part of normal neonatal screening to find out which babies may be more sensitive to heavy metals and chemicals — whether they have “only” mitochondrial dysfunction or mitochondria are functioning completely abnormally — and preventive measures could be taken to protect children.

Related articles:

  • Mitochondrial disorder and autism
  • Supplements for mitochondrial disorders
Resources
  • https://www.sciencedirect.com/science/article/pii/S2352304220300854
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137782/

Omega 3 fatty acid

Omega 3 fatty acid

Autism and Genes, Health, Mitochondria

Omega-3 fatty acids belong to the group of polyunsaturated fatty acids, of which EPA (eicosapentaenoic acid), DHA (docosahexaenoic acid), and alpha-linolenic acid (ALA) are best known. Omega-3 has many properties that help maintain our health, and are an essential bioactive ingredient for children.

omega 3

Omega 3 is mainly an anti-inflammatory agent.

EPA has a strong anti-inflammatory effect and not enough DHA in the diet may reduce the ability to handle sensory input. It only takes a small decrement in brain DHA to produce losses in brain function. (1)

In humans, weak sensorimotor gating is a hallmark of many nervous-system disorders such as schizophrenia or ADHD. Given mounting evidence of the role omega-3s play in the nervous system, there is intense interest in their therapeutic potential, perhaps as a supplement to medicines. For example, people with schizophrenia have lower levels of essential fatty acids, possibly from a genetic variation that results in poor metabolism of these nutrients.

The finding connects low omega-3s to the information-processing problems found in people with schizophrenia; bipolar, obsessive-compulsive, and attention-deficit hyperactivity disorders; Huntington’s disease; and other afflictions of the nervous system.

Omega 3 fatty acid

Omega 3 fatty acid belongs to the group of polyunsaturated fatty acids, of which EPA (eicosapentaenoic acid), DHA (docosahexaenoic acid), and alpha linolenic acid (ALA) are best known. Omega 3 is an essential fatty acid.

Consumption of much marine fish is no longer recommended today due to the pollution of the seas. The most practical solution for consuming EPA, DHA, and GLA is by using high-quality fish oil, borage oil, or evening primrose oil in encapsulated form.

Main physiological effects of histamine intolerance and intestinal problems:

In terms of histamine intolerance, its main effect is its ability to reduce stress and reduce inflammation.

It also helps prevent the development of insulin resistance and has a positive effect on weight loss by helping to break down fat cells.

Physiological effects of Omega 3:

  • Due to their anti-inflammatory effect, it can reduce the risk of many diseases, such as vascular disease, Alzheimer’s disease, and some cancers. But fatty acids can also help treat diabetes, high blood pressure, and skin conditions.
  • Proper intake is essential for athletes due to the maintenance of the cardiovascular system, but it can also improve respiratory function and prevent asthma.
  • It helps the development of the fetus and reduces the incidence of preterm birth. It has a role in developing good visual acuity and mental development in infants.
  • Lower blood cholesterol levels, reducing the risk of atherosclerosis and heart attack.
  • It plays a role in the transport of fats, and the formation of anti-inflammatory prostaglandins, and their beneficial effects on the immune system are also known. And are involved in the structure of the nervous system and cell membranes.
  • Recent research has shown that children consuming omega-3 fatty acids regularly have improved their task-solving and problem-solving skills to understand tasks faster and improve school performance. Achieving optimal intake by children up to 14 is extremely important, as children’s brains develop to the greatest extent by the time they reach this age.
  • Omega 3 prevents the development of kidney stones

 

Other benefits of fish oil according to health problems:

Aging processes

Slows down the aging process.

Cardiovascular system
  • counteracts arrhythmia symptoms.
  • prevents tachycardia.
  • makes it easier to prevent atherosclerosis.
  • Prevents the development of cardiovascular disease.
  • improves heart function.
  • reduces elevated hematocrit levels.
  • lowers blood pressure in hypertensive patients.
  • reduces the development of Raynaud’s disease.
Digestive system
  • reduces the number of relapsing Crohn’s diseases.
  • prevents the formation of gallstones.
Eyes / vision
  • Fish oil prevents the development of macular degeneration (ARMD) in old age.
  • In the case of dry eyes, fish oil is effective in tear production.
  • In people with wolf blindness, fish oil can improve vision in the dark.
  • Fish oil is easy for the development and treatment of retinopathy.
Immune system
  • Children of women who consume fish oil during pregnancy have a lower rate of allergy.
  • Regular consumption of fish oil to avoid the development of autoimmune diseases.
  • Fish oil prevents the development of certain cancers.
  • It has an anti-inflammatory effect on fish oil.
Metabolism
  • enhances athletic performance.
  • reduces the absorption of cholesterol. Fish oil protects muscle fibers from toxic effects (catabolism).
  • prevents tired formation.
  • prevents the development of insulin resistance.
  • helps break down adipose tissue.
  • lowers triglyceride levels.
Musculoskeletal system
  •  reduces back pain.
  •  promotes bone formation.
  •  protects the muscles from the breakdown (catabolism).
  •  Fish oil is an option for the treatment of polymyalgia rheumatica.
  •  relieves the symptoms of rheumatoid arthritis.
Nervous system
  • reduces aggression.
  • have a beneficial effect on the behavior of patients with hyperactivity.
  • prevent the development of Alzheimer’s disease.
  • relieves depression.
  • has the potential for recovery after head injuries.
  •  improves learning ability.
  •  improves memory.
  •  relieves migraine symptoms.
  •  has the potential to relieve the symptoms of Multiple Sclerosis.
  •  is commonly used in the development of Parkinson’s disease.
  •  is used for schizophrenia.
  •  may be suitable for recovery from spinal cord injuries.
  •  alleviates the toxic effects of mental stress.
Respiratory system
  • may be useful in the treatment of acute respiratory distress syndrome (ARSD).
  •  improves respiratory function in asthmatic patients
  • prevents chronic lung disease.
  • easily prevents the development of bronchitis.
  • prevents emphysema.
  • easily improves lung function and reduce the risk of damage from smoking.
Hormanal problems
  • easily relieves menstrual cramps.
  •  reduces the heat waves associated with menopause and relieve depression.
  •  reduces the risk of developing male infertility.
Skin
  • reduces acne sufferers.
  • relieves the symptoms of eczema.
  • relieves itchy skin.
  • improves skin elasticity.
  • easily prevents sunburn in sensitive people.
  • speeds up wound healing.
Resources
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