Diagnosis of SIBO

Diagnosis of SIBO

SIBO

SIBO can be diagnosed with the H2 breath test or the so-called Organix urine test. For abdominal complaints, SIBO-specific symptoms, these are the first two tests that are important to perform.

My point of view is that further testing is also needed, especially if these two are negative. Never be satisfied if the doctoris sending you only for a food intolerance test or diagnosing IBS. There is a reason to find outin the background of both.

What are the possible ways for the diagnosis of SIBO

The diagnosis of SIBO is not so simple. The most common tests are the H2 breath test or the so-called Organix urine test. But more tests should be needed to identify the type of SIBO properly.

The tests proposed are therefore as follows:

 

  • SIBO breath test

A synthetic sugar solution should be drunk and then blow at various intervals into a tube connected to a measuring instrument. The test measures the levels of hydrogen and methane in the breath as the sugar solution passes through different parts of the intestines.

Carbohydrates are the number one food source for bacteria and produce hydrogen and methane during the breakdown of carbohydrates. The tests can only be glucose or lactulose tests, depending on the type of sugar solution used. Glucose can only be tested in the initial stages of the gut because it is then absorbed into the body but gives a clear reaction. However, doctors usually require lactulose tests and if it is negative but symptoms are present require a glucose test.

Another kind of diagnosis of SIBO and other possible tests in the case of abdominal issues

  • Organix-dysbiosis urine test to diagnose SIBO: Organix Comprehensive Profile can easily identify an overgrowth of yeast and bacteria
  • Worm and parasite tests, even for exotic tropical parasites (for example Entamoeba Histolityca), especially if someone travels a lot
  • Intestinal microbiome stool test – Comprehensive stool test. This test is a non-invasive diagnostic assessment that allows practitioners to objectively assess the condition of beneficial and pathogenic bacteria, yeast / fungi, and parasites in the gut. Accurate identification of pathogenic species will greatly facilitate the selection of the most appropriate drugs or natural dietary supplements. With Intestinal microbiome test you will see which intestinal bacteria you need to replace, ie what probiotic supplement you should take.)

…. only the tests mentioned above are done then you can do food allergy tests for being able to follow the proper diet.

Five facts about SIBO

Treatment of SIBO

Symptoms and causes of SIBO

Foods in SIBO

SIBO aggravating factors

Facts about SIBO
SIBO treatment
Symptoms, causes
Foods in SIBO
Aggravatings
Resources
[1]

Wijendran V, Huang MC, Diau GY, et al. Efficacy of dietary arachidonic acid provided as triglyceride or phospholipid as substrates for brain arachidonic acid accretion in baboon neonates. Pediatr Res 2002;51:265-272.

[2]

Goustard-Langelier B, Guesnet P, Durand G,et al. n-3 and n-6 fatty acid enrichment by dietary $sh oil and phospholipid sources in brain cortical areas and nonneural tissues of formula-fed piglets. Lipids 1999;34:5-16.

[3]

Maki KC, Reeves MS, Farmer M, et al. Krill oil supplementation increases plasma concentrations of eicosapentaenoic and docosahexaenoic acids in overweight and obese men and women. Nutr Res 2009;29:609-615.

[4]

Bunea R, El Farrah K, Deutsch L. Evaluation of the effects of Neptune Krill Oil on the clinical course of hyperlipidemia. Altern Med Rev 2004:9:420-428.

[5]

Sampalis F, Bunea R, Pelland MF, et al. Evaluation of the effects of Neptune Krill Oil on the management of premenstrual syndrome and dysmenorrhea. Altern Med Rev 2003;8:171-179.

[6]

Deutsch L. Evaluation of the effect of Neptune Krill Oil on chronic inflammation and arthritic symptoms. J Am Coll Nutr 2007:26:39-48.

[7]

Chang JP, Chen YT, Su KP. Omega-3 polyunsaturated fatty acids (n-3 PUFAs) in cardiovascular diseases (CVDs) and depression: Cardiovasc Psychiatry Neurol 2009;2009:725310. Epub 2009 Sep 27.

[8]

Breslow J. n-3 fatty acids and cardiovascular disease. Am J Clin Nutr 2006;83:1477S-1482S.

[9]

Calzolari I, Fumagalli S, Marchionni N, DiBari M. Polyunsaturated fatty acids and cardiovascular disease. Curr Pharm Des 2009;15:4094-4102.

[10]

No authors listed. Phosphatidylcholine. Altern Med Rev 2002;7:150-154.

[11]

Naguib YM. Antioxidant activities of astaxanthin and related carotenoids. J Agric Food Chem 2000;48:1150-1154.

[12]

Tso P, Drake DS, Black DD, Sabesin SM. Evidence for separate pathways of chylomicron and very low-density lipoprotein assembly and transport by rat small intestine. Am J Physiol 1984;247:G599-G610.

[13]

Amate L, Gil A, Ramirez M. Feeding infant piglets formula with long-chain polyunsaturated fatty acids as triacylglycerols or phospholipids influences the distribution of these fatty acids in plasma lipoprotein fractions. J Nutr 2001;131:1250-1255.

[14]

Tandy S, Chung RW, Wat E, et al. Dietary krill oil supplementation reduces hepatic osteatosis, glycemia, and hypercholesterolemia in high-fat-fed mice. J Agric Food Chem 2009;57:9339-9345.

[15]

Alberts B, Johnson A, Lewis J, et al. Molecular Biology of the Cell. 4th ed. New York, NY: Garland Science; 2002.

[16]

Else PL, Hulbert AJ. Membranes as metabolic pacemakers. Clin Exp Pharmacol Physiol 2003;30:559-564

[17]

Kidd PM. Omega-3 DHA and EPA for cognition, behavior, and mood: clinical findings and structural-functional synergies with cell membrane phospholipids. Altern Med Rev. 2007 Sep;12(3):207-27.

[18]

Konagai C, Yanagimoto K, Hayamizu K, Han L, Tsuji T, Koga Y. Effects of krill oil containing n-3 polyunsaturated fatty acids in phospholipid form on human brain function: a randomized controlled trial in healthy elderly volunteers. Clin Interv Aging. 2013;8:1247-57.

 

[19]

Ebrahimi M, Ghayour-Mobarhan M, Rezaiean S, et al. Omega-3 fatty acid supplements improve the cardiovascular risk profile of subjects with metabolic syndrome, including markers of inflammation and auto-immunity. Acta Cardiol. 2009 Jun;64(3):321-7.

[20]

Derosa G, Cicero AF, Fogari E, et al. Effects of n-3 PUFAs on postprandial variation of metalloproteinases, and inflammatory and insulin resistance parameters in dyslipidemic patients: evaluation with euglycemic clamp and oral fat load. J Clin Lipidol. 2012 Nov-Dec;6(6):553-64.

[21]

Spencer M, Finlin BS, Unal R, et al. Omega-3 fatty acids reduce adipose tissue macrophages in human subjects with insulin resistance. Diabetes. 2013 May;62(5):1709-17.

[22]

Yan Y, Jiang W, Spinetti T, et al. Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation. Immunity. 2013 Jun 27;38(6):1154-63.

[23]

Valensa. FlexPro MD Clinical Trial Overview and Results. (Data on File.) 2011

[24]

McCann JC, Ames BN. Is docosahexaenoic acid, an n-3 long-chain polyunsaturated fatty acid, required for development of normal brain function? An overview of evidence from cognitive and behavioral tests in humans and animals. Am J Clin Nutr 2005;82:281-295.

[25]

Stevens LJ, Zentall SS, Abate ML, et al. Omega-3 fatty acids in boys with behavior, learning, and health problems. Physiol Behav 1996;59:915-920.

    SIBO aggravating factors

    SIBO aggravating factors

    SIBO

     

     

    Any kind of sugar, many type of medicine, stress, condition of gut motility all can aggrevate SIBO. If you are struggeling with abdominal issues but SIBO is not diagnosed try to diminish these factors to reliefe your symptoms.

    I would recomend you to  do some diagnostic tests to find out what is really causing your symptoms and avoid th health consequences of long term abdominal issues. Till the result of the diagnosis avoid these factors listed below

    Which are the most avoidable SIBO aggravating factors

    SIBO aggravating factors can intensify symptoms and worsen the patient’s condition, so it is worth being aware of these factors

    Sugar

    A diet rich in carbohydrates and sugar feeds the bacteria. You don’t just have to think about sugar, baked goods, fruits here. Unfortunately, many other products contain sugar, so it’s worth looking at the ingredient list on salad dressings, pasta sauces, and any suspicious foods. The following should be noted whether this product contains: sucrose, fructose, sucralose, sorbitol, brown rice syrup, corn syrup, fructooligosaccharides, diglycerides, disaccharides, coconut sugar, honey, maple syrup. It is also important to pay attention to the starch content of vegetables.

    SIBO may respond well to carbohydrate elimination, but it may not. Unfortunately, it is the case that someone recovers from SIBO and then the symptoms return again, because it was too early to return foods containing carbohydrates, for example, and it is also the case that after a bowel infection, one can never eat the same foods as before. Lifestyle changes are needed, especially if symptoms return!

    Stress

    Modern life is full of chronic stressors. Longer working hours, an ever-increasing to-do list, and a range of commitments that bombard us from all angles. Stress can lead to SIBO as it directly affects the digestive system. One way to do this is to stop the body from producing stomach acid. When your body is healthy, it secretes stomach acid to kill the ingested bacteria before they enter the small intestine.

    However, if the hormonal system is unbalanced due to increased stress, the body does not produce enough stomach acid to kill the necessary bacteria, allowing the bacteria to enter the small intestine, and stress can cause slowed motility, which also allows the bacteria to multiply in stagnant food in the small intestine. stagnant food.

    Gut Motality

    Once enzymes break down our food, nerves, muscles and neurotransmitters move food throughout our digestive system. The muscles of a healthy digestive system are also able to sweep away undigested food scraps and other substances. A problem with passing food arises when something interferes with peristalsis.

    Such diseases include diabetes, diverticulitis, chron’s disease, multiple sclerosis, stress, but slowed bowel movements are also a first sign of hypothyroidism. In this case, food begins to ferment in the gut and bacteria remain, multiplying, which increases the risk of developing SIBO.

    Medicines

    It is well known that there are medications that affect or disrupt the normal intestinal flora. These are mainly antibiotics and antacids. However, non-steroidal anti-inflammatory drugs and steroids also adversely affect the intestinal flora.

    Antibiotics

    Unfortunately, antibiotics cannot differentiate between “bad” bacteria  and “good” bacteria. Instead, antibiotics destroy everything that gets in their way. When antibiotics kill bacteria in the gut, it disrupts the sensitive ecosystem, causing intestinal dysbiosis or bacterial imbalances. If the number of good bacteria in the gut decreases, the bad bacteria can multiply uncontrollably. When taking antibiotics, the use of probiotics is also very important, but the most reliable protection is provided by probiotics consisting of soil bacteria, because they cannot multiply in the small intestine.

    After taking an antibiotic treatment, it is worth taking a soil probiotic for at least 2 weeks, but this is not the end. Good bacteria need to be restored too. If someone has undergone a strong course of antibiotics, they should also take a wide range of probiotic preparations.

    Antacids

    Although antacids help to suppress the symptoms of reflux, the first protective barrier neutralizes the stomach acid, which is responsible for killing ingested bacteria or pathogens that can reach the small intestine and multiply there, causing symptoms or SIBO. If you take an antacid in the long run, unfortunately you have to reckon with the fact that decreased stomach acid may not kill all the ingested pathogens, so your intestinal system is not completely guarded against intruders.

    Possible consequences of sibo

    The health consequences of SIBO can range from chronic indigestion to autoimmune conditions. It cannot be stressed enough that there is no healthy body without a healthy gut. We talk about a healthy intestinal system if the intestinal microbiome is healthy …. but first you need to know what is an intestinal microbiome and intestinal mucosa?

    Intestinal Microbiome

    The microbiome appears to significantly impact both the immune system and host metabolism. The gut microbiome contains tens of trillion microorganisms. The gut microbiome plays a very important role in your health by helping control digestion and benefiting your immune system and many other aspects of health. An imbalance of unhealthy and healthy microbes in the intestines may contribute to weight gain, high blood sugar, high cholesterol and other disorders.

    Your microbiome starts to develop before you are born. If a mother receives an antibiotic during pregnancy, it can have a lasting effect on the fetal gut microbiome. The child inherits the mother’s microbiome and if it is not healthy then neither the child’s microbiome will be healthy. The child’s microbiome is also affected by the method of birth (caesarean section) and breastfeeding.

     

    Intestinal mucosa

    The two main functions of the gastrointestinal mucosa are concerned with digestion and absorption of dietary nutrients and as a defence against many noxious dietary sub- stances and bacteria. As food passes through the small intestine, nutrients get trapped in the intestinal wall, from where the nutrients enter the bloodstream through the ducts between the intestinal cells, which open and close.

    The cells that make up our intestinal wall are lined with mucous membranes that trap toxins and pathogens so that they cannot enter the bloodstream. There are also special proteins inside this mucosa, called secretory IgA immunoglobulins, antibodies that the immune system produces to fight viruses, bacteria and other infections. They are the first line of defense in the intestinal tract.

    When the secretory IgA recognizes the pathogen passing through the small intestine, it marks it to indicate to the immune system that it needs to be cleared, so the mucus traps the pathogen and clears it from the intestinal tract.

    Formation of Leaky Gut Syndrome

    In fact, the intestinal mucosa damaged by SIBO does not pick up pathogens due to inflammation, the channel between intestinal cells remains open, allowing pathogens and toxins to enter the bloodstream, causing inflammation in other parts of the body, in addition, food sensitivities and allergies develop. This means that if SIBO is left untreated for a long time, autoimmune processes can start.

    Leakage in the gut can also be caused by gluten, as gluten triggers the production of zonulin in the gut. Zonulin is a protein in the small intestine that regulates the opening and closing of the channel between intestinal cells. When zonulin is elevated, it opens the nodes and when it falls down the level closes the nodes. This protein is activated by gluten, which elevates zonulin and opens nodes in the channels between intestinal cells.

    While many suspect celiac disease as the cause of their problems, in reality, SIBO is often present.

    SIBO and Autoimmunity

    When the gut leaks, things like toxins, microbes, undigested food particles can get into the bloodstream from the intestines. Your immune system identifies these “alien invaders” as pathogens and attacks them, often attacking the surrounding tissues as well. This constant influx of pathogens puts the immune system into increased alertness. As the intestinal system leaks, your immune system constantly sends out a wave of inflammation and it soon becomes stressful, weakens, becomes confused, and starts firing less accurately. The immune system turns against the body.

    What kind of autoimmune disease develops depends on which body tissue is attacked by the immune system. If rheumatoid arthritis attacks, arthritis or arthritis can develop. In psoriasis or scleroderma, the skin is attacked. Hashimoto’s and Graves ’diseases are also autoimmune thyroid conditions.

    It is important to treat the underlying dysbiosis that has already become leaking into your body in order to repair the damage and overcome your autoimmune disease. Lack of treatment leads to further damage and the development of other autoimmune diseases. Once an autoimmune disease has developed, another is three times more likely to develop another.

    If you have SIBO and / or leaking bowel disease and are still diagnosed with autoimmune disease, start treating your SIBO and leaking bowel syndrome immediately. If you read on, you will also get advice on this.

    Vitamin and mineral deficiency

    SIBO can also lead to vitamin and mineral deficiencies. In particular, SIBO can interfere with the absorption of nutrients. Absorption disorders occur for a variety of reasons, including changes in the mucous membranes and bile salts. Malabsorption usually leads to nutrient deficiencies such as B12 deficiency, which can cause fatigue, anemia, diarrhea and headaches. However, the absorption disorder caused by SIBO can also prevent the absorption of vitamins A, D, E and K as well as iron.

    SKIN PROBLEMS

    Your skin is the largest organ in your body and is full of nerves that transmit important information about your environment by sensing pain, texture, and temperature. Your skin is made up of three layers: the epidermis, the dermis and the hypodermis. The epidermis, which is the outermost layer, is the outer line of defense. In the second layer of skin, the dermis, there are nerve endings that send signals to the brain to know that something is itchy, sore, hot, cold, and so on.

    The hypodermis, which is the innermost layer, contains blood vessels that are connected to the other blood vessels in the body. In the case of Sibo, if it passes through the intestines, toxins and pathogens enter the bloodstream and circulate in the body. Rash, painful pre-oral dermatitis, rosacea, and other skin problems often occur due to the permeable bowel. If you have stubborn skin symptoms, go to a gastroenterologist or SIBO test first rather than to a dermatologist.

    HISTAMINE INTOLERANCE

    Histamine intolerance almost always indicates that something is wrong inside. Many people with histamine intolerance often refer to their SIBO symptoms as food intolerance.
    The professional view is that SIBO is the leading cause in the development of histamine intolerance. In many cases, when SIBO is treated and becomes asymptomatic, symptoms of histamine intolerance remain but there is no acceptable position on this yet.

    The point is that the immune system reacts to foreign substances entering the bloodstream as “invaders,” so it produces histamine to neutralize intruders and triggers inflammatory. Certain species of bacteria, including L. casei and L. bul garicus, have been shown to enhance histamine production. Because of this, if you suspect you have SIBO, don’t start taking probiotics blindly because the oil could be on fire. Recommendation for probiotics can be found in the “Treatment of SIBO” article.

    In case of inflammation of the gut, the amount of the DAO enzyme produced in the gut, which is responsible for breaking down histamine, is reduced. This in turn results in elevated levels of histamine in the blood. As you consume more and more histamine-rich or DAO-blocking foods, your DAO level will not be enough to control your histamine levels, so you will eventually develop intolerance.

    If you have or suspect histamine intolerance, you may also want to read the “Histamine Intolerance” article, or the “Treatment of histamine intolerance/MCAS

    Five facts about SIBO

    Treatment of SIBO

    Symptoms and causes of SIBO

    Diagnosis of SIBO

    Foods in SIBO

    Facts about SIBO
    SIBO treatment
    Symptoms, causes
    Diagnosis
    Foods in SIBO
    Resources
    [1]

    Wijendran V, Huang MC, Diau GY, et al. Efficacy of dietary arachidonic acid provided as triglyceride or phospholipid as substrates for brain arachidonic acid accretion in baboon neonates. Pediatr Res 2002;51:265-272.

    [2]

    Goustard-Langelier B, Guesnet P, Durand G,et al. n-3 and n-6 fatty acid enrichment by dietary $sh oil and phospholipid sources in brain cortical areas and nonneural tissues of formula-fed piglets. Lipids 1999;34:5-16.

    [3]

    Maki KC, Reeves MS, Farmer M, et al. Krill oil supplementation increases plasma concentrations of eicosapentaenoic and docosahexaenoic acids in overweight and obese men and women. Nutr Res 2009;29:609-615.

    [4]

    Bunea R, El Farrah K, Deutsch L. Evaluation of the effects of Neptune Krill Oil on the clinical course of hyperlipidemia. Altern Med Rev 2004:9:420-428.

    [5]

    Sampalis F, Bunea R, Pelland MF, et al. Evaluation of the effects of Neptune Krill Oil on the management of premenstrual syndrome and dysmenorrhea. Altern Med Rev 2003;8:171-179.

    [6]

    Deutsch L. Evaluation of the effect of Neptune Krill Oil on chronic inflammation and arthritic symptoms. J Am Coll Nutr 2007:26:39-48.

    [7]

    Chang JP, Chen YT, Su KP. Omega-3 polyunsaturated fatty acids (n-3 PUFAs) in cardiovascular diseases (CVDs) and depression: Cardiovasc Psychiatry Neurol 2009;2009:725310. Epub 2009 Sep 27.

    [8]

    Breslow J. n-3 fatty acids and cardiovascular disease. Am J Clin Nutr 2006;83:1477S-1482S.

    [9]

    Calzolari I, Fumagalli S, Marchionni N, DiBari M. Polyunsaturated fatty acids and cardiovascular disease. Curr Pharm Des 2009;15:4094-4102.

    [10]

    No authors listed. Phosphatidylcholine. Altern Med Rev 2002;7:150-154.

    [11]

    Naguib YM. Antioxidant activities of astaxanthin and related carotenoids. J Agric Food Chem 2000;48:1150-1154.

    [12]

    Tso P, Drake DS, Black DD, Sabesin SM. Evidence for separate pathways of chylomicron and very low-density lipoprotein assembly and transport by rat small intestine. Am J Physiol 1984;247:G599-G610.

    [13]

    Amate L, Gil A, Ramirez M. Feeding infant piglets formula with long-chain polyunsaturated fatty acids as triacylglycerols or phospholipids influences the distribution of these fatty acids in plasma lipoprotein fractions. J Nutr 2001;131:1250-1255.

    [14]

    Tandy S, Chung RW, Wat E, et al. Dietary krill oil supplementation reduces hepatic osteatosis, glycemia, and hypercholesterolemia in high-fat-fed mice. J Agric Food Chem 2009;57:9339-9345.

    [15]

    Alberts B, Johnson A, Lewis J, et al. Molecular Biology of the Cell. 4th ed. New York, NY: Garland Science; 2002.

    [16]

    Else PL, Hulbert AJ. Membranes as metabolic pacemakers. Clin Exp Pharmacol Physiol 2003;30:559-564

    [17]

    Kidd PM. Omega-3 DHA and EPA for cognition, behavior, and mood: clinical findings and structural-functional synergies with cell membrane phospholipids. Altern Med Rev. 2007 Sep;12(3):207-27.

    [18]

    Konagai C, Yanagimoto K, Hayamizu K, Han L, Tsuji T, Koga Y. Effects of krill oil containing n-3 polyunsaturated fatty acids in phospholipid form on human brain function: a randomized controlled trial in healthy elderly volunteers. Clin Interv Aging. 2013;8:1247-57.

     

    [19]

    Ebrahimi M, Ghayour-Mobarhan M, Rezaiean S, et al. Omega-3 fatty acid supplements improve the cardiovascular risk profile of subjects with metabolic syndrome, including markers of inflammation and auto-immunity. Acta Cardiol. 2009 Jun;64(3):321-7.

    [20]

    Derosa G, Cicero AF, Fogari E, et al. Effects of n-3 PUFAs on postprandial variation of metalloproteinases, and inflammatory and insulin resistance parameters in dyslipidemic patients: evaluation with euglycemic clamp and oral fat load. J Clin Lipidol. 2012 Nov-Dec;6(6):553-64.

    [21]

    Spencer M, Finlin BS, Unal R, et al. Omega-3 fatty acids reduce adipose tissue macrophages in human subjects with insulin resistance. Diabetes. 2013 May;62(5):1709-17.

    [22]

    Yan Y, Jiang W, Spinetti T, et al. Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation. Immunity. 2013 Jun 27;38(6):1154-63.

    [23]

    Valensa. FlexPro MD Clinical Trial Overview and Results. (Data on File.) 2011

    [24]

    McCann JC, Ames BN. Is docosahexaenoic acid, an n-3 long-chain polyunsaturated fatty acid, required for development of normal brain function? An overview of evidence from cognitive and behavioral tests in humans and animals. Am J Clin Nutr 2005;82:281-295.

    [25]

    Stevens LJ, Zentall SS, Abate ML, et al. Omega-3 fatty acids in boys with behavior, learning, and health problems. Physiol Behav 1996;59:915-920.

    Gut and skin

    Gut and skin

    Digestion, Health, Microbiome and Gut health, Natural skincare, SIBO

    The link between gut and skin health

     

    If you have skin rashes or eczematous symptoms, you should never think it is a genetic condition.

    If you have long-term, chronic symptoms, you should not only see a dermatologist or switch to natural cosmetics but also remember that digestive problems and internal parasites could be behind the external symptoms.

    In nutritional studies, the skin has long been considered an indicator of intestinal issues and an imbalance of intestinal flora.

    To have clear, healthy skin, you should first regenerate your gut.

    Epidemiological studies show a clear link between intestinal problems and skin diseases.

    When skin problems do not respond properly to skin care treatments, the source of the problem is actually in the gut. A poorly functioning gut system can potentially exacerbate or lead to pre-existing skin conditions. Acne, rosacea, and perioral dermatitis are ten times more likely to occur with small intestinal bacterial infections (SIBO). Skin rashes occur in 14% of patients with ulcerative colitis and 24% with Crohn’s disease. Mucosal lesions, alopecia, and vitiligo are also more common in gluten sensitivity. Skin problems and acne may occur due to increased intestinal permeability (leaky gut) in inflammatory bowel disease.

    Studies have shown that intestinal inflammation and dysbiosis can impair the skin’s protective function. This condition, in turn, leads to a decrease in the number of antimicrobial peptides produced in the skin and may increase the severity of certain infections as part of the skin’s inflammatory response

    The intestinal flora influences the health of the skin

    The condition of the intestinal flora affects the health of the skin. The so-called neuropeptide substance P is produced in the intestine, brain, and skin and plays an essential role in the condition of the skin. An altered gut microbiome releases higher neuropeptide P levels in the gut and the skin. Higher levels of neuropeptide P affect lipid production and fatty acid profiles in tissues and can influence sebum production and fatty acid composition of sebum. Several studies have already demonstrated the positive effects of probiotics on the skin.

    Gut-skin axis

    “The GSA describes the relationship where the gut can influence skin health owing to its immunological and metabolic properties.52 Although it is difficult to strictly attribute a cause-and-effect relationship between the gut microbiome and dermatologic conditions, multiple studies support a connection between them with several cutaneous diseases being associated with GI disorders and vice versa.”(1)

    Several studies have already demonstrated the beneficial effects of probiotics on the skin. Fermented dairy products have a positive effect on intestinal flora, while unfermented dairy products can promote acne breakouts. However, be careful with fermented products if you suffer from SIBO. Oral probiotics reduce inflammation and systemic oxidative stress markers, which are locally elevated in acne. However, if you do not know anything about your microbiome, it is recommended to take only high-quality soil-based probiotics.

    “Gut microbiota influence the pathophysiology of acne via cross-talk between intestinal commensal bacteria and the mTOR pathway ()” (2)

    A well-balanced, nutrient-rich diet is critical to maintaining a healthy gut. If you do not have any particular intestinal problems, you can take probiotic supplements to increase the versatility of your intestinal flora.

    Quercetin, a powerful antioxidant, and a miracle molecule can still be beneficial. Since I have been taking Quercetin regularly, I have not had a single pimple, although I am sure that my intestinal flora is not 100% perfect.

    What can you do to improve your digestion and skin?

    • Avoid dairy, soy, gluten, and rapidly absorbable carbohydrates for at least 1-2 months.
    • Take probiotics daily. Preferably something that has been studied and proven to be effective. If you have intestinal problems, take only soil-based probiotics.
    • In the case of digestive problems, take regular “digestive enzymes ” to help your digestion, which will relieve your heavy stomach immediately after a large meal. If you do not take a digestive supplement, incorporate apple cider vinegar into your daily routine, preferably the unfiltered variety. After a meal, a tablespoon will help digest the food. It is important to support digestion with natural supplements when altered intestinal flora and impaired digestion slow down the digestion of food because, in this case, there is stagnation in the small intestine, which causes many unpleasant symptoms and inflammation.
    • Move around whenever you can!
    • I am thinking of something other than going to the gym every day. However, you should walk as much as possible if you do not have time to exercise. Introduce a 15-minute workout at a faster pace 3x per week to work your muscles and speed up your metabolism.
    • Take evening primrose oil, as its gamma-linolenic acid content reduces the symptoms of eczema, and take omega-3 capsules (1000 mg ) 2-3 times a day to reduce inflammatory processes.

    Stick to the above for at least 2-3 months, and follow a diet high in fiber, and you will surely see the change!

    Resources
    [1]

    https://www.sciencedirect.com/science/article/abs/pii/S0738081X21001930

    [2]

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048199/

    [3]

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916842/

    [4]

    https://www.dermatologytimes.com/view/gut-bacteria-linked-to-inflammatory-skin-disease

    [5]

    https://pubmed.ncbi.nlm.nih.gov/33924414/

    [6]

    Deutsch L. Evaluation of the effect of Neptune Krill Oil on chronic inflammation and arthritic symptoms. J Am Coll Nutr 2007:26:39-48.

    [7]

    https://pubmed.ncbi.nlm.nih.gov/27554239/

    [8]

    https://pubmed.ncbi.nlm.nih.gov/33921772/

    [9]

    https://pubmed.ncbi.nlm.nih.gov/33540138/

    [10]

    https://www.eurekalert.org/news-releases/903431

    [11]

    Demirel Ogut N. Link Between the Gut and Inflammatory Skin Disease Exposed. Accessed May 11, 2021. Published online May 7, 2021. https://www.eurekalert.org/pub_releases/2021-05/sc-tro050621.php

    [12]

    Stocum, Linda. “Gut Bacteria Linked to Inflammatory Skin Disease.” https://www.dermatologytimes.com/, 11 May 2021, www.dermatologytimes.com/view/gut-bacteria-linked-to-inflammatory-skin-disease.

    [13]

    Juhl, Christian R, et al. “Dairy Intake and Acne Vulgaris: A Systematic Review and Meta Analysis of 78,529 Children, Adolescents, and Young Adults.” Nutrients, U.S. National Library of Medicine, 9 Aug. 2018, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115795/.

    [14]

    Sanz, Yolanda. “Effects of a Gluten-Free Diet on Gut Microbiota and Immune Function in Healthy Adult Humans.” Gut Microbes, U.S. National Library of Medicine, 2010, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023594/.

    [15]

    Acne Vulgaris – Statpearls – NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK459173/.

    [16]

    Demirel Ogut N. Link Between the Gut and Inflammatory Skin Disease Exposed. Accessed May 11, 2021. Published online May 7, 2021. https://www.eurekalert.org/pub_releases/2021-05/sc-tro050621.php

    [17]

    Stocum, Linda. “Gut Bacteria Linked to Inflammatory Skin Disease.” https://www.dermatologytimes.com/, 11 May 2021, www.dermatologytimes.com/view/gut-bacteria-linked-to-inflammatory-skin-disease.

    [18]

    Juhl, Christian R, et al. “Dairy Intake and Acne Vulgaris: A Systematic Review and Meta Analysis of 78,529 Children, Adolescents, and Young Adults.” Nutrients, U.S. National Library of Medicine, 9 Aug. 2018, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115795/.

    [19]

    Sanz, Yolanda. “Effects of a Gluten-Free Diet on Gut Microbiota and Immune Function in Healthy Adult Humans.” Gut Microbes, U.S. National Library of Medicine, 2010, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023594/.